Subtitle
A Pooled Toxicity Analysis of Moderately Hypofractionated Proton Beam Therapy and Intensity-Modulated Radiation Therapy in Early Stage Prostate Cancer Patients.
Subtitle
A Pooled Toxicity Analysis of Moderately Hypofractionated Proton Beam Therapy and Intensity-Modulated Radiation Therapy in Early Stage Prostate Cancer Patients.
Proto therapy Time
July 2021
Executive summary
This multi-institutional study compared late toxicity profiles of a total of 1850 patients, including 1282 IMRT and 568 PBT. Overall toxicity rates were low, with the majority of patients experiencing no late GU (56.6%, n=1048) or late GI (74.4%, n=1377) toxicity. No difference was seen in the rates of late toxicity between the groups, with late Grade 3+ GU toxicity of 2.0% vs 3.9%, and late Grade 2+ GI toxicity of 14.6% vs 4.7%, for the PBT and IMRT cohorts respectively.
Key content topics
Top cancer treatments
Related contents
Proton Therapy Publication
March 2024
A multicenter high-quality data registry for advanced proton therapy approaches: the POWER registry.
Webinar
March 29, 2023
Hypofractionation in Proton Therapy: radiobiological bases and clinical applications
Roberto
Orecchia
Barbara
Jereczek
Daniela
Alterio
Dante
Amelio
Jiri
Kubes
Proton Therapy Publication
March 2023
A retrospective study of adjuvant proton radiotherapy for breast cancer after lumpectomy: a comparison of conventional-dose and hypofractionated dose.
Proton Therapy Publication
November 2022
Hypofractionated proton therapy for non-small cell lung cancer: Ready for prime time? A systematic review and meta-analysis.
Proton Therapy Publication
May 2022
The Role of Hypofractionation in Proton Therapy.
Proton Therapy Publication
April 2022
Outcome after Radiotherapy for Vestibular Schwannomas – Differences in Tumor Control, Symptoms and Quality of Life after Radiotherapy with Photon versus Proton Therapy.
Proton Therapy Publication
December 2021
FLASH Radiotherapy Using Single-Energy Proton PBS Transmission Beams for Hypofractionation Liver Cancer: Dose and Dose Rate Quantification.
Proton Therapy Publication
November 2021
Clinical Effectiveness of Hypofractionated Proton Beam Therapy for Liver Metastasis From Breast Cancer.
Proton Therapy Publication
November 2021
Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advanced head and neck cancer patients [PIRATES]: A Phase I safety and feasibility trial of MRI-guided adaptive particle radiotherapy.